34 of 34 papers
2026
- APOBEC2 deficiency disrupts hematopoietic lineage commitment, resulting in emergence of dual identity lymphocytes in mice and humans
Moris Amro E, … Imbusch CD, … Papavasiliou FN
Proceedings of the National Academy of Sciences of the United States of America
- Epigenetic dysregulation of IRF9 drives excessive interferon signaling in COPD
Llamazares-Prada M, … Imbusch CD, … Jurkowska RZ
EMBO molecular medicine
2025
- Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation
Staehle HF, … Imbusch CD, … Jutzi JS
Cell death & disease
- Polyamines regulate adaptive antitumor immunity by functional specialization of regulatory T cells
Bündgen G, … Imbusch C, … Bopp T
Immunity
- DNA hypomethylation traits define human regulatory T cells in cutaneous tissue and identify their blood recirculating counterparts
Beumer N, … Imbusch CD, … Feuerer M
Nature immunology
- Identifying similar populations across independent single cell studies without data integration
González-Velasco O, … Imbusch CD, … Brors B
NAR genomics and bioinformatics
- Bemcentinib as monotherapy and in combination with low-dose cytarabine in acute myeloid leukemia patients unfit for intensive chemotherapy: a phase 1b/2a trial
Loges S, … Imbusch CD, … Gjertsen BT
Nature communications
2024
- Multiple myeloma long-term survivors exhibit sustained immune alterations decades after first-line therapy
Lutz R, … Imbusch CD, … Haas S
Nature communications
- SOX10 mediates glioblastoma cell-state plasticity
Man KH, … Imbusch CD, … Radlwimmer B
EMBO reports
- Single-cell chromatin accessibility and transposable element landscapes reveal shared features of tissue-residing immune cells
Simon M, … Imbusch CD, … Feuerer M
Immunity
- Diagnostic leukapheresis reveals distinct phenotypes of NSCLC circulating tumor cells
Rieckmann LM, … Imbusch CD, … Janning M
Molecular cancer
- The effector program of human CD8 T cells supports tissue remodeling
Delacher M, … Imbusch CD, … Feuerer M
The Journal of experimental medicine
2023
- Chronic chromosome instability induced by Plk1 results in immune suppression in breast cancer
Kandala S, … Imbusch CD, … Sotillo R
Cell reports
- Spatially Resolved Multi-Omics Single-Cell Analyses Inform Mechanisms of Immune Dysfunction in Pancreatic Cancer
Yousuf S, … Imbusch CD, … Roth S
Gastroenterology
- High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD
Schwartz U, … Imbusch CD, … Jurkowska RZ
The EMBO journal
- Integrated single-cell profiling dissects cell-state-specific enhancer landscapes of human tumor-infiltrating CD8(+) T cells
Riegel D, … Imbusch CD, … Schmidl C
Molecular cell
2022
- Pathologic responses in oligometastatic NSCLC patients treated with neoadjuvant immune checkpoint blockade with and without chemotherapy followed by surgery
Boch T, … Imbusch CD, … Loges S
Lung cancer (Amsterdam, Netherlands)
2021
- AXL Inhibition Represents a Novel Therapeutic Approach in BCR-ABL Negative Myeloproliferative Neoplasms
Beitzen-Heineke A, … Imbusch CD, … Loges S
HemaSphere
- Lorlatinib Induces Durable Disease Stabilization in a Pancreatic Cancer Patient with a ROS1 p.L1950F Mutation: Case Report
Velthaus JL, … Imbusch CD, … Loges S
Oncology research and treatment
- Deconvolution of sarcoma methylomes reveals varying degrees of immune cell infiltrates with association to genomic aberrations
Simon M, … Imbusch CD
Journal of translational medicine
- Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
Delacher M, … Imbusch CD, … Feuerer M
Immunity
- Aggressive PDACs Show Hypomethylation of Repetitive Elements and the Execution of an Intrinsic IFN Program Linked to a Ductal Cell of Origin
Espinet E, … Imbusch CD, … Trumpp A
Cancer discovery
2020
- Quantitative Proteomics Identifies TCF1 as a Negative Regulator of Foxp3 Expression in Conventional T Cells
Delacher M, … Imbusch CD, … Feuerer M
iScience
- Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF
Delacher M, … Imbusch CD, … Feuerer M
Immunity
2019
- Rbpj expression in regulatory T cells is critical for restraining T(H)2 responses
Delacher M, … Imbusch CD, … Feuerer M
Nature communications
- Generation of Whole Genome Bisulfite Sequencing Libraries from Very Low DNA Input
Weichenhan D, … Imbusch CD, … Plass C
Methods in molecular biology (Clifton, N.J.)
2018
- Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters
Behjati Ardakani F, … Imbusch CD, … Schulz MH
Epigenetics & chromatin
2017
- Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
Delacher M, … Imbusch CD, … Feuerer M
Nature immunology
- The whole-genome landscape of medulloblastoma subtypes
Northcott PA, … Imbusch CD, … Lichter P
Nature
- DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
Brocks D, … Imbusch CD, … Plass C
Nature genetics
2016
- Epigenomic Profiling of Human CD4(+) T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development
Durek P, … Imbusch CD, … Polansky JK
Immunity
- DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia
Oakes CC, … Imbusch CD, … Plass C
Nature genetics
2014
- Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
Northcott PA, … Imbusch CD, … Pfister SM
Nature
2013
- Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
Jones DT, … Imbusch CD, … International Cancer Genome Consortium PedBrain Tumor Project
Nature genetics