Teamleader for Computational Oncoimmunology at DKFZ
The main focus of our team is on the downstream analysis of various single cell assays such as: scRNA-seq, scATAC-seq, scTCR-seq, CITE-seq and other technologies in health and disease systems. We seek to robustly identify and describe cell populations to aid basic research and enable clinical translation. In addition we apply deconvolution methods to combine bulk epigenetic and transcriptomic with single cell data.
01/2014 - 01/2017
Bioinformatician at Division of Applied Bioinformatics at DKFZ
Analysis of NGS data, method developement to distinguish 'Driver' and 'Passenger' mutations in cancer
04/2012 - 12/2013
Data Engineer at Data Management Group at DKFZ
Management and submission of German ICGC project results
Deployment and curation of a local cBio instance
06/2011 - 03/2012
Junior Consultant at Intershop Communications
Developing of new visualization for Customer Information Center (CIC), R&D for data migration based on Oracle.
09/2010 - 05/2011
Scientific Assistant at Max Planck Institute for Chemical Ecology
Data management using Biomart within the department of Entomology.
Programming: Python, R, Java, Bash
Databases: SQL (PostgreSQL)
Workflow systems: Snakemake
NGS assays: scRNA-seq, scATAC-seq, scTCR, CITE-seq, (T)WGBS, WGS/WES, RNA-seq, 450k, EPIC array
OS: Linux, macOS
Virtualization: Docker, Singularity
Version control: Git, Mercurial, SVN
Teamleader: Supervising PhD, Master, Bachelor students as well as internships
Projects: Mangement of project aspects within DEEP, de.NBI, ICGC, Pancan, EUCANcan
02/2017 - 05/2019
PhD at Divison of Applied Bioinformatics / DKFZ (Prof. Benedikt Brors)
Title: "Epigenetic and transcriptomic characterization of tissue resident regulatory T cells"
Diplom at Department of Entomology / Max Planck Institute for Chemical Ecology (Prof. David G. Heckel)
Title: "Homology-guided improvement of DNA sequence assembly"
10/2004 - 06/2010